顺,顺-1,3,5-环己三羧酸甲酯合成路线 （共 6 条）
反应条件
Multistep reaction. Yields of byproduct given;
参考文献
Askew; Ballester; Buhr; Jeong; Jones; Parris; Williams; Rebek Jr.
Journal of the American Chemical Society, 1989 , vol. 111, # 3 p. 1082 - 1090
参考文献
van der Zanden; de Vries
Recueil des Travaux Chimiques des Pays-Bas, 1948 , vol. 67, p. 998,1002
反应条件
hydrogen; acetic acid; platinum(IV) oxide
T=25°C; P=1034.3 - 2585.7 Torr; 3.5 h;
参考文献
Nielsen, Arnold T.; Christian, Stephen L.; Moore, Donald W.; Gilardi, Richard D.; George, Clifford F.
Journal of Organic Chemistry, 1987 , vol. 52, # 9 p. 1656 - 1662
反应条件
thionyl chloride
T=20°C; 4 h;
参考文献
Chuang, Tsung-Hsun; Fang, Jim-Min
Journal of the Chinese Chemical Society, 2001 , vol. 48, # 2 p. 193 - 200
反应条件
1: 88 percent / HCl(g) / 1 h / y
2: 95 percent / H2, acetic acid / platinum oxide / 3.5 h / 25 °C / 1034.3 - 2585.7 Torr
View Scheme
参考文献
Nielsen, Arnold T.; Christian, Stephen L.; Moore, Donald W.; Gilardi, Richard D.; George, Clifford F.
Journal of Organic Chemistry, 1987 , vol. 52, # 9 p. 1656 - 1662
反应条件
1: trimethyl cis,cis-cyclohexane-1,3,5-tricarboxylate With lithium diisopropyl amide in diethyl ether
T=0°C; 2 h;
2: dimethyl sulfate in diethyl ether
T=20°C; 12 h;
参考文献
Chuang, Tsung-Hsun; Fang, Jim-Min
Journal of the Chinese Chemical Society, 2001 , vol. 48, # 2 p. 193 - 200
