3-溴丙酮酸乙酯合成路线

参考文献

Houssin, Raymond; Pommery, Jean; Salauen, Marie-Catherine; Deweer, Sophie; Goossens, Jean-Francois; Chavatte, Philippe; Henichart, Jean-Pierre
Journal of Medicinal Chemistry, 2002 , vol. 45, # 2 p. 533 - 536

115-08-2硫代甲酰胺+

70-23-53-溴丙酮酸乙酯

14527-43-64-噻唑甲酸乙酯

参考文献

Erne et al.
Helvetica Chimica Acta, 1951 , vol. 34, p. 143,147

70-23-53-溴丙酮酸乙酯+

2521-24-64-氯硫代苯甲酰胺

61786-00-32-(4-氯苯基)-噻唑-4-羧酸乙酯

参考文献

Zia, Mehwash; Akhtar, Tashfeen; Hameed, Shahid; Al-Masoudi, Najim A.
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2012 , vol. 67, # 7 p. 747 - 758

70-23-53-溴丙酮酸乙酯+

42590-97-62-甲氧基苯硫代甲酰胺

115299-16-62-(2-甲氧基苯基)-噻唑-4-羧酸乙酯

参考文献

Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, , vol. 67, # 7 p. 747 - 758

126533-95-72-(4-吗啉基)-4-噻唑羧酸乙酯

参考文献

Abbott Laboratories
Patent: US5461067 A1, 1995 ;
US 5461067 A

14294-10-14-吗啉硫代甲酰胺+

70-23-53-溴丙酮酸乙酯

126533-95-72-(4-吗啉基)-4-噻唑羧酸乙酯

参考文献

Kempf, Dale J.; Sham, Hing L.; Marsh, Kennan C.; Flentge, Charles A.; Betebenner, David; Green, Brian E.; McDonald, Edith; Vasavanonda, Sudthida; Saldivar, Ayda; Wideburg, Norman E.; Kati, Warren M.; Ruiz, Lisa; Zhao, Chen; Fino, Lynnmarie; Patterson, Jean; Molla, Akhteruzzaman; Plattner, Jacob J.; Norbeck, Daniel W.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 4 p. 602 - 617

19798-80-22-氨基-4-氯吡啶+

70-23-53-溴丙酮酸乙酯

1204501-38-17-氯-咪唑并[1,2-a]吡啶-2-羧酸乙酯

参考文献

FENG, Yangbo; CHEN, Yen Ting; SESSIONS, Hampton; MISHRA, Jitendra K.; CHOWDHURY, Sarwat; YIN, Yan; LOGRASSO, Philip; LUO, Jun-Li; BANNISTER, Thomas; SCHROETER, Thomas
Patent: WO2011/50245 A1, 2011 ;
Location in patent: Page/Page column 108 ;
WO 2011/050245 A1

70-23-53-溴丙酮酸乙酯

1204501-38-17-氯-咪唑并[1,2-a]吡啶-2-羧酸乙酯

参考文献

JANSSEN RandD IRELAND; COOYMANS, Ludwig Paul; HU, Lili; JONCKERS, Tim Hugo Maria; RABOISSON, Pierre Jean-Marie Bernard; TAHRI, Abdellah; VAN HOOF, Steven Maurice Paula; VENDEVILLE, Sandrine Marie Helene
Patent: WO2012/80451 A1, 2012 ;

参考文献

Despax, Corine; Navech, Jaques
Tetrahedron Letters, 1990 , vol. 31, # 31 p. 4471 - 4472

参考文献

Despax, Corine; Navech, Jaques
Tetrahedron Letters, 1990 , vol. 31, # 31 p. 4471 - 4472