3-溴丙酮酸乙酯合成路线

参考文献

Luraschi; Arena; Sacchi; Laneri; Abignente; Avallone; D'Amico; Berrino; Rossi
Farmaco, 1997 , vol. 52, # 4 p. 213 - 217

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; ABEYWARDANE, Asitha; BRUNETTE, Steven Richard; BURKE, Michael Jason; KIRRANE, Thomas Martin, Jr.; MAN, Chuk Chui; MARSHALL, Daniel Richard; PADYANA, Anil Kumar; RAZAVI, Hossein; SIBLEY, Robert; SMITH KEENAN, Lana Louise; SNOW, Roger John; SORCEK, Ronald John; TAKAHASHI, Hidenori; TAYLOR, Steven John; TURNER, Michael Robert; YOUNG, Erick Richard Roush; ZHANG, Qiang; ZHANG, Yunlong; ZINDELL, Renee M.
Patent: WO2014/14874 A1, 2014 ;
Location in patent: Page/Page column 201; 202 ;

70-23-53-溴丙酮酸乙酯

124730-53-65,6-二氢-4H-吡咯并[3,2,1-ij]喹啉-1-羧酸乙酯

参考文献

Van Wijngaarden; Hamminga; Van Hes; Standaar; Tipker; Tulp; Mol; Olivier; De Jonge
Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3693 - 3699

70-23-53-溴丙酮酸乙酯+

126-81-85,5-二甲基-1,3-环己二酮

121625-78-36,6-二甲基-4-氧代-4,5,6,7-四氢苯并呋喃-3-羧酸

参考文献

NOVARTIS AG
Patent: WO2008/101905 A1, 2008 ;
Location in patent: Page/Page column 20-21 ;
WO 2008/101905 A1

70-23-53-溴丙酮酸乙酯+

3471-13-43-羟基-5,5-二甲基环己-2-烯-1-酮

121625-78-36,6-二甲基-4-氧代-4,5,6,7-四氢苯并呋喃-3-羧酸

参考文献

Nagarajan, Kuppuswamy; Talwalker, Purnachard K.; Goud, A. Nagana; Shah, Rashmi K.; Shenoy, Sharada J.; Desai, Narasimha D.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 1113 - 1123

70-23-53-溴丙酮酸乙酯+

27366-72-9二甲胺基硫代乙酰胺盐酸盐

199599-68-3

参考文献

PFIZER INC.
Patent: EP807633 A2, 1997 ;

Title/Abstract Full Text Show Details
Pfizer Inc
Patent: US6323208 B1, 2001 ;

Title/Abstract Full Text Show Details
Pfizer Inc.
Patent: US5962457 A1, 1999 ;

70-23-53-溴丙酮酸乙酯+

34329-67-4

25438-22-6

参考文献

Brookes,P. et al.
Journal of the Chemical Society, 1960 , p. 925 - 931

541-35-5+

70-23-53-溴丙酮酸乙酯

14819-39-7

参考文献

Geiger,S. et al.
Chimica Therapeutica, 1966 , vol. 1, p. 425 - 437

参考文献

BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2006/71752 A1, 2006 ;
Location in patent: Page/Page column 83 ;
WO 2006/071752 A1

1532-84-9+

70-23-53-溴丙酮酸乙酯

69707-18-2

参考文献

Kuz'menko, T. A.; Kuz'menko, V. V.; Simonov, A. M.; Simkin, B. Ya.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1980 , vol. 16, # 12 p. 1255 - 1260
Khimiya Geterotsiklicheskikh Soedinenii, 1980 , vol. 16, # 12 p. 1656 - 1661