1: 80 percent / triethylamine / acetone / 1 h / Heating 2: 82 percent / H2 / 10percent Pd/C / ethyl acetate / 760 Torr 3: 1.) sodium nitrite, concd. H2SO4, 2.) cuprous chloride, concd. HCl / 1.) acetic acid, 0 deg C, 2.) acetic acid, a) from 5 deg C to RT, 1 h, b) 80 deg C, 30 min View Scheme
参考文献
Atkinson, David C.; Godfrey, Keith E.; Meek, Bernard; Saville, John F.; Stillings, Michael R.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1353 - 1360
