2,3,5,6-四氟苯胺合成路线 （共 23 条）
反应条件
tri-tert-butyl phosphine; sodium t-butanolate; bis(dibenzylideneacetone)-palladium(0) in toluene T=85°C; Buchwald-Hartwig coupling; 15.5 h;
参考文献
Acemoglu, Murat; Allmendinger, Thomas; Calienni, John; Cercus, Jacques; Loiseleur, Olivier; Sedelmeier, Gottfried H.; Xu, David
Tetrahedron, 2004 , vol. 60, # 50 p. 11571 - 11586
反应条件
pyridine T=120°C; 2 h;
参考文献
Van Zandt, Michael C.; Doan, Brian; Sawicki, Diane R.; Sredy, Janet; Podjarny, Alberto D.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 7 p. 2006 - 2008
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2004/48314 A1, 2004 ;
Location in patent: Page 25 ;
