5-苯基-3,4-二氢-2H-吡咯合成路线 （共 67 条）
反应条件
pyrrolidine; (S,S)-ethylene-1,2-bis(η5-4,5,6,7-tetrahydro-1-indenyl)titanium difluoride; phenyl silane in tetrahydrofuran; methanol 12 h; Ambient temperature;
参考文献
Verdaguer, Xavier; Lange, Udo E. W.; Reding, Matthew T.; Buchwald, Stephen L.
Journal of the American Chemical Society, 1996 , vol. 118, # 28 p. 6784 - 6785
反应条件
D-glucose; (S)-imine reductase from Streptomyces sp. GF3546; NADPH in aq. phosphate buffer; N,N-dimethyl-formamide T=30°C; pH=7; 18 h; Enzymatic reaction; Kinetics; enantioselective reaction;
参考文献
Quinto, Tommaso; Schwizer, Fabian; Zimbron, Jeremy M.; Morina, Albert; Koehler, Valentin; Ward, Thomas R.
ChemCatChem, 2014 , vol. 6, # 4 p. 1010 - 1014
反应条件
n-butyllithium; (R)-lt;2,2'-biphenyldiylbis(3,4-dimethylcyclopentadienyl)gt;titanium dichloride; hydrogen in hexane; toluene T=80°C; P=112509 Torr; 12 h;
参考文献
Ringwald, Markus; Stuermer, Rainer; Brintzinger, Hans H.
Journal of the American Chemical Society, 1999 , vol. 121, # 7 p. 1524 - 1527
反应条件
D-glucose; (S)-imine reductase from Streptomyces sp. GF3546; NADPH in aq. phosphate buffer; N,N-dimethyl-formamide T=30°C; pH=7; 18 h; Enzymatic reaction; Kinetics; enantioselective reaction;
参考文献
Quinto, Tommaso; Schwizer, Fabian; Zimbron, Jeremy M.; Morina, Albert; Koehler, Valentin; Ward, Thomas R.
ChemCatChem, 2014 , vol. 6, # 4 p. 1010 - 1014
反应条件
1: NaBH4 / ethanol 2: 83 percent / TsOH / xylene 3: 92 percent / conc. H2SO4 / trifluoroacetic acid / 20 °C 4: BH2-THF View Scheme
参考文献
Schulze, Oliver; Schmidt, Ulrich; Voss, Juergen; Nebeling, Bruno; Adiwidjaja, Gunadi; Scharwaechter, Klaus
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 8 p. 2105 - 2111
反应条件
2,2′-Bis[(1H-inden-3′-yl)-hexanyl]titaniumdichloride in tetrahydrofuran T=60°C; 3 h; Inert atmosphere;
参考文献
Gruber-Woelfler, Heidrun; Lichtenegger, Georg J.; Neubauer, Christoph; Polo, Eleonora; Khinast, Johannes G.
Dalton Transactions, 2012 , vol. 41, # 41 p. 12711 - 12719
反应条件
sodium tetrahydroborate in methanol; water T=20°C;
参考文献
Dunsmore, Colin J.; Carr, Reuben; Fleming, Toni; Turner, Nicholas J.
Journal of the American Chemical Society, 2006 , vol. 128, # 7 p. 2224 - 2225
反应条件
Ru(Η6-cymene)(MsDPEN)(BArF); hydrogen in dichloromethane T=40°C; P=38002.6 Torr; 10 h; Inert atmosphereAutoclave; optical yield given as percent eeenantioselective reaction;
参考文献
Organic Letters, , vol. 13, # 16 p. 4348 - 4351
反应条件
Ru(Η6-cymene)(MsDPEN)(BArF); hydrogen in methanol T=40°C; P=38002.6 Torr; 10 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Organic Letters, , vol. 13, # 16 p. 4348 - 4351
反应条件
carbon monoxide; [(Ph3P)2]Ni(CO)2 in ethanol; water
T=125°C; P=10343 Torr; 20 h;
参考文献
Campi, Eva M.; Jackson, W. Roy
Journal of Organometallic Chemistry, 1996 , vol. 523, # 2 p. 205 - 209
