5-苯基-3,4-二氢-2H-吡咯合成路线 （共 67 条）
反应条件
in toluene
8 h; UV-irradiationInert atmosphere;
参考文献
Muthukrishnan, Sivaramakrishnan; Sankaranarayanan, Jagadis; Klima, Rodney F.; Pace, Tamara C. S.; Bohne, Cornelia; Gudmundsdottir, Anna D.
Organic Letters, 2009 , vol. 11, # 11 p. 2345 - 2348
反应条件
triethylsilane; trifluoroacetic acid
参考文献
Brinner, Kristin M.; Ellman, Jonathan A.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 11 p. 2109 - 2113
反应条件
sodium methylate in methanol
T=20°C; 1 h;
参考文献
Nenajdenko; Pronin; Balenkova
Russian Chemical Bulletin, 2007 , vol. 56, # 2 p. 336 - 344
反应条件
toluene-4-sulfonic acid in benzene
Heating;
参考文献
Wills, Max T.; Wills, Irene E.; Dollen, Lawrence Von; Butler, Barry L.; Porter, John; Anderson, Arthur G.
Journal of Organic Chemistry, 1980 , vol. 45, # 12 p. 2489 - 2498
反应条件
1:
2: With hydrogen cation
Further stages.;
参考文献
Nenajdenko; Pronin; Balenkova
Russian Chemical Bulletin, 2007 , vol. 56, # 2 p. 336 - 344
反应条件
1.1: Mg; I2 / tetrahydrofuran / 1 h / 20 °C
1.2: tetrahydrofuran / 12 h / -48 °C
2.1: 50 percent / Et3SiH; aq. TFA
View Scheme
参考文献
Brinner, Kristin M.; Ellman, Jonathan A.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 11 p. 2109 - 2113
反应条件
1: 1.) KOH, 2.) HCl / 1.) ethanol/water, 6 h, reflux
2: p-Toluenesulfonic acid / benzene / Heating
View Scheme
参考文献
Wills, Max T.; Wills, Irene E.; Dollen, Lawrence Von; Butler, Barry L.; Porter, John; Anderson, Arthur G.
Journal of Organic Chemistry, 1980 , vol. 45, # 12 p. 2489 - 2498
反应条件
1: dimethylformamide
2: 1.) KOH, 2.) HCl / 1.) ethanol/water, 6 h, reflux
3: p-Toluenesulfonic acid / benzene / Heating
View Scheme
参考文献
Wills, Max T.; Wills, Irene E.; Dollen, Lawrence Von; Butler, Barry L.; Porter, John; Anderson, Arthur G.
Journal of Organic Chemistry, 1980 , vol. 45, # 12 p. 2489 - 2498
反应条件
in diethyl ether
T=25°C; 12 h;
参考文献
Zezza, Charles A.; Smith, Michael B.; Ross, Betsy A.; Arhin, Akwasi; Cronin, Patricia L. E.
Journal of Organic Chemistry, 1984 , vol. 49, # 23 p. 4397 - 4399
反应条件
sodium hydride in tetrahydrofuran
参考文献
Schulze, Oliver; Schmidt, Ulrich; Voss, Juergen; Nebeling, Bruno; Adiwidjaja, Gunadi; Scharwaechter, Klaus
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 8 p. 2105 - 2111
