1: N-ethyl-piperazine; 4,6-dichloro-pyrimidine With potassium carbonate in isopropyl alcohol T=20°C; 18 h; 2: 4-chloro-6-(4-ethyl-piperazin-1-yl)-pyrimidine; hydrazine in isopropyl alcohol 22 h; Heating / reflux;