反应条件
1: triethylamine / CH2Cl2 / 1.) 0 deg C, 30 min, 2.) room temperature, 2 h
2: 80 percent / NaI / tetrahydrofuran / 10 h
3: 1.05 g / tetrabutyl ammonium bromide, aq. NaOH / CH2Cl2 / 1.) 0 deg C, 3 h, 2.) room temperature, 6 h
4: 1.) NaH / 1.) ether, -5-0 deg C, 10 min, 2.) ether, 10-15 deg C, 3 h
5: conc. HCl / CH2Cl2; diethyl ether / 0.25 h / 20 °C
View Scheme
参考文献
Rao, A.V. Rama; Deshpande, V.H.; Reddy, S. Pulla
Synthetic Communications, 1984 , vol. 14, # 5 p. 469 - 476
