反应条件
1: 55 percent / 1.) NaH, 2.) n-BuLi / 1.) THF, HMPA, -12 - 0 deg C -> 25 deg C; 25 deg C, 20 min, 2.) THF, HMPA, hexane, -15 - 0 deg C -> 25 deg C, 25 deg C, 0.5 h, 3.) -15 - 4 deg C, 30 min, RT, 3 h
2: 80 percent / KOH / methanol; H2O / 10 h / Heating
3: 75 percent / PCC / CH2Cl2 / 6 h / Ambient temperature
View Scheme
参考文献
Reddy, R. Thimma; Nayak, U. R.
Synthetic Communications, 1986 , vol. 16, # 6 p. 713 - 722
