反应条件
1: 41 g / l'acide para-toluene sulfonique / benzene / 5 h / Heating
2: potasse / H2O / 25 deg C, 0.5 h then 75 deg C, 0.5 h
3: 93 percent / HCl / CHCl3
4: Et3N / tetrahydrofuran / -20 - 0 °C
5: 1.) (i-C3H7)2NLi / 1.) ether, -60 deg C, 18 h, 2.) 20 deg C, 2 h, HCl
6: 87 percent / H2SO4 / acetone; H2O / 4 h / 40 - 45 °C
View Scheme
参考文献
Moreau, J.-L.; Couffignal, R.; Arous-Chtara, R.
Tetrahedron, 1981 , vol. 37, p. 307 - 310
