环丙烷-1,2-二羧酸二甲酯合成路线 （共 5 条）
反应条件
1: 1. NaOH, 2. HCl 2: 80 percent / Ac2O 3: 1.175 gradC, 2. Ac2O, 200 gradC 4: 90 percent / LiAlH4 5: 1. MCPBA, 2. Cope elimination, 170 gradC View Scheme
参考文献
Tufariello, Joseph J.; Milowsky, Arnold S.; Al-Nuri, Mohammed; Goldstein, Steven
Tetrahedron Letters, 1987 , vol. 28, # 3 p. 267 - 270
反应条件
1. NaOH, 2. HCl; Yield given. Multistep reaction;
参考文献
Tufariello, Joseph J.; Milowsky, Arnold S.; Al-Nuri, Mohammed; Goldstein, Steven
Tetrahedron Letters, 1987 , vol. 28, # 3 p. 267 - 270
反应条件
hydrogenchloride; copper(ll) bromide; lithium diisopropyl amide in tetrahydrofuran; hexane
T=-78°C; var. temp., var. metal salt, var. molar equiv., var. solvent additive; Product distribution;
参考文献
Chung, Sung Kee; Dunn, Larson B.
Journal of Organic Chemistry, 1983 , vol. 48, # 7 p. 1125 - 1127
参考文献
Tufariello, Joseph J.; Milowsky, Arnold S.; Al-Nuri, Mohammed; Goldstein, Steven
Tetrahedron Letters, 1987 , vol. 28, # 3 p. 267 - 270
反应条件
potassium carbonate
1.)CHCl3, H2O, 0 deg C, 2.) 24h, ambient temp.; Yield given. Multistep reaction;
参考文献
McBride, Bill J.; Garst, Michael E.; Hopkins, Mark
Journal of Organic Chemistry, 1984 , vol. 49, p. 1824 - 1825
