5-溴-2-甲基氨基-3-硝基吡啶合成路线 （共 8 条）
反应条件
in tetrahydrofuran T=0°C; 0.5 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2010/261714 A1, 2010 ;
Location in patent: Page/Page column 89 ;
反应条件
methylamine in isopropyl alcohol
参考文献
Boehringer Ingelheim Pharma KG
Patent: US6200976 B1, 2001 ;
US 6200976 B1
反应条件
pyridinium hydrobromide perbromide; acetic acid T=20°C; 2 h;
参考文献
Linstroem, Stefan; Eriksson, Mikael; Grivas, Spiros
Acta Chemica Scandinavica, 1993 , vol. 47, # 8 p. 805 - 812
反应条件
1: 86 percent / ethanol / 10 h / Heating 2: 60 percent / pyridinium bromide perbromide, AcOH / 2 h / 20 °C View Scheme
参考文献
Acta Chemica Scandinavica, , vol. 47, # 8 p. 805 - 812
反应条件
sulfuric acid; nitric acid Yield given;
参考文献
Acta Chemica Scandinavica, , vol. 47, # 8 p. 805 - 812
反应条件
1: 2.) NaBH4 2: H2SO4, HNO3 View Scheme
参考文献
Acta Chemica Scandinavica, , vol. 47, # 8 p. 805 - 812
参考文献
Chemische Berichte, , vol. 61, p. 1230
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 60, p. 975
反应条件
1: With iron; acetic acid in water
T=20°C; 0.666667 h;
2: With sodium hydroxide; water
参考文献
AMGEN INC.
Patent: WO2009/17822 A2, 2009 ;
Location in patent: Page/Page column 79; 80 ;
WO 2009/017822 A2
