1-溴-3-乙基-2-硝基苯合成路线 （共 5 条）
反应条件
1: With hydrogen bromide; sodium nitrite in water
T=0°C; 0.166667 h;
2: With hydrogen bromide; copper; copper(II) sulfate in water
T=80°C; 0.5 h;
参考文献
Buehler, Sigrid; Lagoja, Irene; Giegrich, Heiner; Stengele, Klaus-Peter; Pfleiderer, Wolfgang
Helvetica Chimica Acta, 2004 , vol. 87, # 3 p. 620 - 659
反应条件
1.1: 75 percent / SnCl2*2H2O; HCl / methanol / cooling
2.1: aq. HBr; NaNO2 / H2O / 0.17 h / 0 °C
2.2: 58 percent / CuSO4*5H2O; Cu; aq. HBr / H2O / 0.5 h / 80 °C
View Scheme
参考文献
Buehler, Sigrid; Lagoja, Irene; Giegrich, Heiner; Stengele, Klaus-Peter; Pfleiderer, Wolfgang
Helvetica Chimica Acta, 2004 , vol. 87, # 3 p. 620 - 659
反应条件
1.1: aq. HNO3; H2SO4 / 72 h / 20 °C
1.2: 8 percent / NaOH / ethanol / 0.67 h / Heating
2.1: NaNO2; H2SO4 / 0.67 h / 20 °C
2.2: 52 percent / ethanol / 1 h / Heating
3.1: 75 percent / SnCl2*2H2O; HCl / methanol / cooling
4.1: aq. HBr; NaNO2 / H2O / 0.17 h / 0 °C
4.2: 58 percent / CuSO4*5H2O; Cu; aq. HBr / H2O / 0.5 h / 80 °C
View Scheme
参考文献
Buehler, Sigrid; Lagoja, Irene; Giegrich, Heiner; Stengele, Klaus-Peter; Pfleiderer, Wolfgang
Helvetica Chimica Acta, 2004 , vol. 87, # 3 p. 620 - 659
反应条件
1.1: NaNO2; H2SO4 / 0.67 h / 20 °C
1.2: 52 percent / ethanol / 1 h / Heating
2.1: 75 percent / SnCl2*2H2O; HCl / methanol / cooling
3.1: aq. HBr; NaNO2 / H2O / 0.17 h / 0 °C
3.2: 58 percent / CuSO4*5H2O; Cu; aq. HBr / H2O / 0.5 h / 80 °C
View Scheme
参考文献
Buehler, Sigrid; Lagoja, Irene; Giegrich, Heiner; Stengele, Klaus-Peter; Pfleiderer, Wolfgang
Helvetica Chimica Acta, 2004 , vol. 87, # 3 p. 620 - 659
反应条件
hydrogenchloride; ethanol; tin(ll) chloride
参考文献
Kondo; Uyeo
Chemische Berichte, 1937 , vol. 70, p. 1087,1091
Show Details
Uyeo
Yakugaku Zasshi, 1937 , vol. 57, p. 839,846
Chem. Zentralbl., 1938 704
