6-氯-4-羟基-3-喹啉羧酸乙酯合成路线 (共 7 条)
反应条件
Gould-Jacob reaction; 0.0666667 h; Irradiation;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 41, # 3 p. 650 - 652
反应条件
in diphenylether 1 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 22 p. 5471 - 5484
反应条件
1: 1 h / Heating 2: various solvent(s) / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 22 p. 6443 - 6450
反应条件
1: ethanol / Reflux 2: diphenylether / Reflux View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 4 p. 1448 - 1452
参考文献
Ukrainets, I. V.; Taran, S. G.; Gorokhova, O. V.; Marusenko, N. A.; Kovalenko, S. N.; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995 , vol. 31, # 2 p. 167 - 175
Khimiya Geterotsiklicheskikh Soedinenii, 1995 , # 2 p. 195 - 203
反应条件
1: 2 N aq. NaOH / 1.5 h / Heating 2: 1.5 g / diphenyl ether / 1 h / Heating 3: 90 percent / POCl3 / 1 h / 140 °C View Scheme
参考文献
Riegel et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1264
反应条件
trichlorophosphate T=110°C; 0.333333 h; Inert atmosphere;
参考文献
Journal of Medicinal Chemistry, , vol. 55, # 7 p. 3578 - 3582