4-溴-Alpha-环丙基苯甲醇合成路线 （共 4 条）
反应条件
1: in tetrahydrofuran
T=5 - 15°C; 0.25 h;
2: With water; ammonium chloride in tetrahydrofuran
参考文献
BIOPROJET; SUN PHARMA ADVANCED RESEARCH COMPANY LTD
Patent: WO2008/152149 A1, 2008 ;
Location in patent: Page/Page column 38 ;
WO 2008/152149 A1
反应条件
magnesium
1.) THF, 0 deg C, 60 min, 2.) 25 deg C, 16 h; Yield given. Multistep reaction;
参考文献
McCormick, J. P.; Fitterman, Alan S.; Barton, Donald L.
Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4708 - 4712
反应条件
lithium aluminium tetrahydride
参考文献
Hanack,M. et al.
Chemische Berichte, 1963 , vol. 96, p. 2532 - 2536
反应条件
2: LiAlH4
View Scheme
参考文献
Hanack,M. et al.
Chemische Berichte, 1963 , vol. 96, p. 2532 - 2536
