1-(2,4-二羟基-6-甲基苯基)乙酮合成路线 (共 23 条)
反应条件
magnesium
2.) benzene, reflux, 18 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Crombie, Leslie; Games, David E.; James, Alun W. G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1996 , # 22 p. 2715 - 2724
参考文献
Desai; Mavani
Proceedings - Indian Academy of Sciences, Section A, 1949 , vol. <A> 29, p. 269,270
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Desai; Mavani
Current Science, 1941 , vol. 10, p. 524
Proceedings - Indian Academy of Sciences, Section A, 1947 , vol. <A> 25, p. 353,356
参考文献
Desai; Ekhlas
Proceedings - Indian Academy of Sciences, Section A, 1938 , # 8 p. 194,199
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Desai; Vakil
Proceedings - Indian Academy of Sciences, Section A, 1940 , vol. 12, p. 391,394
反应条件
pyridine
T=220°C; 4 h; Microwave irradiation;
参考文献
Zhou, Ting; Shi, Qian; Lee, Kuo Hsing
Tetrahedron Letters, 2010 , vol. 51, # 33 p. 4382 - 4386
反应条件
pyridine
T=150°C; 10 h;
参考文献
Suzuki, Madoka; Yu, Donglei; Morris-Natschke, Susan L.; Smith, Philip C.; Lee, Kuo-Hsiung
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 21 p. 6852 - 6858
反应条件
1: 0.1 g / orthophosphoric acid / petroleum ether / 6 h / 30 - 35 °C
2: 0.16 g / DDQ / benzene / 10 h / Heating
View Scheme
参考文献
Ahluwalia, V. K.; Mukherjee, Keya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 9 p. 880 - 882
反应条件
1: propionic acid ethyl ester With sodium hydride in tetrahydrofuran
Reflux;
2: 1-(2,4-dihydroxy-6-methylphenyl)ethanone in tetrahydrofuran; isopropyl alcohol
Reflux;
参考文献
Zhou, Ting; Ohkoshi, Emika; Shi, Qian; Bastow, Kenneth F.; Lee, Kuo-Hsiung
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 9 p. 3219 - 3222
反应条件
trichlorophosphate; benzene
参考文献
Shah; Shah
Journal of the Chemical Society, 1938 , p. 1424,1427
参考文献
Shah; Shah
Journal of the Chemical Society, 1938 , p. 1424,1427
参考文献
Shah; Shah
Journal of the Chemical Society, 1938 , p. 1424,1427