1,3-苯并间二氧杂环戊烯-5-丙醇合成路线 （共 29 条）
参考文献
Pfizer Inc.
Patent: US6288120 B1, 2001 ;
反应条件
dipyridinium dichromate 1.) CH2Cl2, room temp., 12 h, 2.) CH2Cl2, Et2O, r.t., 2 h;
参考文献
Barreiro, Eliazer J.; Costa, Paulo R. R.; Coelho, Fernando A. S.; Farias, Florence M. C. de
Journal of Chemical Research, Miniprint, 1985 , # 7 p. 2301 - 2332
反应条件
jones reagent in acetone T=0°C; 1 h;
参考文献
Lima, Patricia C.; Lima, Lidia M.; Da Silva, Kelli Cristine M.; Leda, Paulo Henrique O.; De Miranda, Ana Luisa P.; Fraga, Carlos A. M.; Barreiro, Eliezer J.
European Journal of Medicinal Chemistry, 2000 , vol. 35, # 2 p. 187 - 203
反应条件
complex boron hydride with tetrahydrofurane in tetrahydrofuran
1 h; Heating / reflux;
参考文献
Texas Biotechnology Corp.
Patent: US6342610 B2, 2002 ;
Location in patent: Page column 128 ;
US 6342610 B2
反应条件
hydrogen; palladium on activated charcoal in methanol
P=760 Torr; 36 h;
参考文献
Datta, Swarup; Odedra, Arjan; Liu, Rai-Shung
Journal of the American Chemical Society, 2005 , vol. 127, # 33 p. 11606 - 11607
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
1.5 h; Heating;
参考文献
Bode; Doyle; Protopopova; Zhou
Journal of Organic Chemistry, 1996 , vol. 61, # 26 p. 9146 - 9155
反应条件
1: With dimethylsulfide borane complex in dichloromethane
T=20°C; 5 h; DarknessInert atmosphere;
2: With dihydrogen peroxide; sodium hydroxide in water
T=20°C; 20 h;
参考文献
Romeiro, Luiz A.S.; Da Silva Ferreira, Marcos; Da Silva, Leandro L.; Castro, Helena C.; Miranda, Ana L.P.; Silva, Claudia L.M.; Noel, Franois; Nascimento, Jessica B.; Araujo, Claudia V.; Tibirica, Eduardo; Barreiro, Eliezer J.; Fraga, Carlos A.M.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 3000 - 3012
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=20°C;
参考文献
LOTUS PHARMACEUTICAL CO., LTD.
Patent: US2009/143397 A1, 2009 ;
Location in patent: Page/Page column 5; 6-7 ;
反应条件
peracetic acid; sodium acetate; potassium bromide in acetic acid
T=20°C; 24 h;
参考文献
Fauvel, Anne; Deleuze, Herve; Landais, Yannick
European Journal of Organic Chemistry, 2005 , # 18 p. 3900 - 3910
反应条件
in tetrahydrofuran; methanol
参考文献
Chan, Ming Fai; Kogan, Timothy; Verner, Erik Joel; Kois, Adam; Balaji, Vitukudi Narayanaiyengar
Patent: US2002/95041 A1, 2002 ;
