(2-羟基苄基)三苯基溴化膦合成路线 （共 37 条）
反应条件
1: 85 percent / pyridine / CHCl3 / 2 h / Heating
2: 83 percent / triethylamine / toluene / 1.25 h / Heating
View Scheme
参考文献
Guillaumel; Royer; Le Corre; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 5 p. 431 - 436
反应条件
1: 73 percent / pyridine / CHCl3 / 2 h / Heating
2: 64 percent / triethylamine / toluene / 0.75 h / Heating
View Scheme
参考文献
Guillaumel; Royer; Le Corre; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 5 p. 431 - 436
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine; dicyclohexyl-carbodiimide in dichloromethane; toluene
1.) room temperature, 24 h, 2.) 85 deg C, 5 h 15 min;
参考文献
McKittrick, Brian A.; Stevenson, Robert
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 4 p. 709 - 712
反应条件
triethylamine in dichloromethane; toluene
T=110°C; 1 h; microwave irradiation;
参考文献
De Luca, Lidia; Giacomelli, Giampaolo; Nieddu, Giammario
Journal of Organic Chemistry, 2007 , vol. 72, # 10 p. 3955 - 3957
反应条件
sodium methylate in methanol; toluene
1.) room temp, 10 min; 2.) reflux, 30 min;
参考文献
Begasse, B.; Corre, M. Le
Tetrahedron, 1980 , vol. 36, p. 3409 - 3412
反应条件
in xylene
0.5 h; Heating;
参考文献
Capuano, Lilly; Ahlhelm, Alfred; Hartmann, Herbert
Chemische Berichte, 1986 , vol. 119, # 6 p. 2069 - 2074
反应条件
1: 68 percent / NEt3 / CH2Cl2 / 3 h
2: 72 percent / NEt3 / xylene / 2 h
View Scheme
参考文献
Capuano, Lilly; Ahlhelm, Alfred; Hartmann, Herbert
Chemische Berichte, 1986 , vol. 119, # 6 p. 2069 - 2074
反应条件
sodium methylate in methanol; toluene
1.) room temp, 10 min; 2.) reflux, 30 min;
参考文献
Begasse, B.; Corre, M. Le
Tetrahedron, 1980 , vol. 36, p. 3409 - 3412
反应条件
triethylamine in toluene
参考文献
Canon Kabushiki Kaisha
Patent: US5733476 A1, 1998 ;
反应条件
1: pyridine / CHCl3 / 3 h / Heating
2: 70 percent / triethylamine / toluene / 3 h / Heating
View Scheme
参考文献
Hercouet, A.; Corre, M. Le
Tetrahedron, 1981 , vol. 37, # 16 p. 2867 - 2874
