1-(氯乙酰基)-4-(3-氯苯基)哌嗪盐酸盐合成路线 （共 3 条）
反应条件
4-(N,N-dimethlyamino)pyridine; 1,2-dichloro-ethane; triethylamine; chloroacetic acid in 4-(dicyanomethylene)-2-methyl-6-(4-dimethylaminostyryl)-4H-pyran
参考文献
PAJOUHESH, Hassan; PAJOUHESH, Hossein; DING, Yanbing; TAN, Jason; GRIMWOOD, Mike; BELARDETTI, Francesco; KAUL, Ramesh
Patent: US2008/280900 A1, 2008 ;
反应条件
triethylamine in chloroform
T=0°C; 2 h;
参考文献
Oshiro; Sakurai; Tanaka; Kikuchi; Hirose; Tottori
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2014 - 2023
反应条件
lithium aluminium tetrahydride in tetrahydrofuran; diethyl ether
T=40°C; 0.5 h;
参考文献
Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, Roberto; Rapposelli, Simona; Digiacomo, Maria; Vanni, Michael; Balsamo, Aldo
Journal of Medicinal Chemistry, 2008 , vol. 51, # 23 p. 7602 - 7613
