(S)-2-甲基-1,4-丁二醇合成路线 （共 57 条）
反应条件
1: Raney Ni / ethanol / 12 h / 20 °C 2: 85 percent / LAH / diethyl ether / 6 h / 20 °C View Scheme
参考文献
Heterocycles, , vol. 55, # 8 p. 1505 - 1518
反应条件
1: 0.140 g / NaBH4 / methanol / 0.25 h / 0 °C 2: NaBH3CN / aq. formic acid View Scheme
参考文献
Helvetica Chimica Acta, , vol. 73, p. 1258 - 1275
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Gazzetta Chimica Italiana, , vol. 105, p. 233 - 245
反应条件
hydrogenchloride; sodium cyanoborohydride in acetic acid 3 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Helvetica Chimica Acta, , vol. 73, p. 1258 - 1275
反应条件
sodium cyanoborohydride in formic acid Yield given;
参考文献
Helvetica Chimica Acta, , vol. 73, p. 1258 - 1275
反应条件
hydrogenchloride; sodium cyanoborohydride in acetic acid Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Helvetica Chimica Acta, , vol. 73, p. 1258 - 1275
反应条件
1.1: methanol / 2 h / 0 - 40 °C 2.1: hydrogenchloride; water / diethyl ether / 0.17 h 3.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C 3.2: 0 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 22, # 1 p. 26 - 30
反应条件
1.1: hydrogenchloride; water / diethyl ether / 0.17 h 2.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C 2.2: 0 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 22, # 1 p. 26 - 30
反应条件
1.1: sulfuric acid / 3 h / Reflux 2.1: methanol / 2 h / 0 - 40 °C 3.1: hydrogenchloride; water / diethyl ether / 0.17 h 4.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C 4.2: 0 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 22, # 1 p. 26 - 30
反应条件
1.1: sulfuric acid / water 2.1: sulfuric acid / 3 h / Reflux 3.1: methanol / 2 h / 0 - 40 °C 4.1: hydrogenchloride; water / diethyl ether / 0.17 h 5.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C 5.2: 0 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 22, # 1 p. 26 - 30
