4-苯基-5-(3,4,5-三甲氧基苯基)-2,4-二氢-3H-1,2,4-三唑-3-硫酮合成路线 （共 5 条）
反应条件
sodium hydroxide
3 h; Heating;
参考文献
Maxwell, James R.; Wasdahl, Dan A.; Wolfson, Alan C.; Stenberg, Virgil I.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1565 - 1570
反应条件
1: 85 percent / 1 h / Heating
2: 85 percent / 5percent NaOH / H2O / 4 h / Heating
View Scheme
参考文献
Mazzone; Bonina; Reina; Blandino
Farmaco, Edizione Scientifica, 1981 , vol. 36, # 3 p. 181 - 196
反应条件
1: H2NNH2*H2O / 6 h / Heating
2: ethanol / 4 h / Heating
3: 93 percent / aq. NaOH / 3 h / Heating
View Scheme
参考文献
Maxwell, James R.; Wasdahl, Dan A.; Wolfson, Alan C.; Stenberg, Virgil I.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1565 - 1570
反应条件
1: conc. H2SO4 / 20 h / Heating
2: H2NNH2*H2O / 6 h / Heating
3: ethanol / 4 h / Heating
4: 93 percent / aq. NaOH / 3 h / Heating
View Scheme
参考文献
Maxwell, James R.; Wasdahl, Dan A.; Wolfson, Alan C.; Stenberg, Virgil I.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1565 - 1570
反应条件
1: ethanol / 4 h / Heating
2: 93 percent / aq. NaOH / 3 h / Heating
View Scheme
参考文献
Maxwell, James R.; Wasdahl, Dan A.; Wolfson, Alan C.; Stenberg, Virgil I.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1565 - 1570
