5-(6-羟基-2,5,7,8-四甲基色满-2-基)-2-甲基戊酸甲酯合成路线 （共 4 条）
反应条件
boron trifluoride diethyl etherate in 1,4-dioxane
T=110°C;
参考文献
Pope, Simon A.S.; Burtin, Guillaume E.; Clayton, Peter T.; Madge, David J.; Muller, David P.R.
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 5 p. 1337 - 1343
反应条件
1: 76 percent / sulphuric acid / 2 h / Heating
2: 81 percent / tetrahydrofuran / 2 h / 0 °C
3: 80 percent / BF3*Et2O / dioxane / 110 °C
View Scheme
参考文献
Pope, Simon A.S.; Burtin, Guillaume E.; Clayton, Peter T.; Madge, David J.; Muller, David P.R.
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 5 p. 1337 - 1343
反应条件
1: 81 percent / tetrahydrofuran / 2 h / 0 °C
2: 80 percent / BF3*Et2O / dioxane / 110 °C
View Scheme
参考文献
Pope, Simon A.S.; Burtin, Guillaume E.; Clayton, Peter T.; Madge, David J.; Muller, David P.R.
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 5 p. 1337 - 1343
反应条件
sodium hydroxide in methanol; water
2 h; Heating;
参考文献
Pope, Simon A.S.; Burtin, Guillaume E.; Clayton, Peter T.; Madge, David J.; Muller, David P.R.
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 5 p. 1337 - 1343
