4-乙炔基-α,α,α-三氟甲苯合成路线 (共 50 条)
反应条件
(alkaline hydrolysis);
参考文献
Tetrahedron Letters, , p. 5209 - 5212
反应条件
1: 100 percent / copper(I) iodide; triethylamine / PdCl2(PPh3)2 / 12 h / 100 °C 2: 3.9 g / aq. NaOH / methanol / 2 h / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 124, # 8 p. 1584 - 1585
反应条件
zinc dibromide; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=25°C; Substitution;
参考文献
Organic Letters, , vol. 2, # 23 p. 3687 - 3689
反应条件
potassium carbonate in methanol; acetonitrile T=40°C; Sonogashira Cross-Coupling;
参考文献
Catalysis Communications, , vol. 47, p. 40 - 44
反应条件
tetra-n-butylammonium fluoride trihydrate in diethyl ether
参考文献
Journal of the American Chemical Society, , vol. 107, # 19 p. 5443 - 5447
反应条件
n-butyllithium in diethyl ether
参考文献
Bulletin of the Chemical Society of Japan, , vol. 61, # 5 p. 1625 - 1632
反应条件
caesium carbonate; dimethyl sulfoxide T=115°C; 12 h;
参考文献
Tetrahedron Letters, , vol. 52, # 9 p. 992 - 994
反应条件
caesium carbonate in ethanol T=0°C;
参考文献
Organic Letters, , vol. 14, # 16 p. 4070 - 4073
反应条件
1: Br2 / diethyl ether / 2 h / -10 °C 2: 50 percent / KOH / H2O; diethyl ether / 180 - 220 °C View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 9 p. 3216 - 3245