3-(4-氨基苯基)-n-甲基丙酰胺合成路线 （共 4 条）
反应条件
5 palladium on charcoal; hydrogen in tetrahydrofuran
6 h;
参考文献
Lu, Chenshu; Tang, Ke; Li, Yan; Li, Peng; Lin, Ziyun; Yin, Dali; Chen, Xiaoguang; Huang, Haihong
European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 351 - 360
反应条件
1: thionyl chloride / 2 h / 0 °C / |Reflux
2: triethylamine / dichloromethane / 8 h / 0 - 20 °C
3: hydrogen; 5 palladium on charcoal / tetrahydrofuran / 6 h
View Scheme
参考文献
Lu, Chenshu; Tang, Ke; Li, Yan; Li, Peng; Lin, Ziyun; Yin, Dali; Chen, Xiaoguang; Huang, Haihong
European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 351 - 360
反应条件
1: triethylamine / dichloromethane / 8 h / 0 - 20 °C
2: hydrogen; 5 palladium on charcoal / tetrahydrofuran / 6 h
View Scheme
参考文献
Lu, Chenshu; Tang, Ke; Li, Yan; Li, Peng; Lin, Ziyun; Yin, Dali; Chen, Xiaoguang; Huang, Haihong
European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 351 - 360
反应条件
1: piperidine / pyridine / 4 h / 90 °C
2: thionyl chloride / 2 h / 0 °C / |Reflux
3: triethylamine / dichloromethane / 8 h / 0 - 20 °C
4: hydrogen; 5 palladium on charcoal / tetrahydrofuran / 6 h
View Scheme
参考文献
Lu, Chenshu; Tang, Ke; Li, Yan; Li, Peng; Lin, Ziyun; Yin, Dali; Chen, Xiaoguang; Huang, Haihong
European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 351 - 360
