2,6-二甲基-4-羟基苯甲醛合成路线 （共 22 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 1 h;
参考文献
Coppola, Gary M.; Gong, Yongjin
Organic Preparations and Procedures International, 2007 , vol. 39, # 2 p. 199 - 202
反应条件
hydrogenchloride; aluminium trichloride; benzene und anschliessend mit wss.HCl;
参考文献
Journal of the American Chemical Society, , vol. 68, p. 1862
反应条件
potassium hydroxide in water T=60°C; Reimer-Tiemann; 18 h;
参考文献
Yamada; Toyota; Takakura; Ishimaru; Sugawara
New Journal of Chemistry, 2001 , vol. 25, # 5 p. 667 - 669
反应条件
silver trifluoromethanesulfonate in dichloromethane T=0°C; 0.5 h; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 78, # 7 p. 3438 - 3444
反应条件
1: 1.) HCl, 2.) AlCl3, HCl / 1.) benzene, 25 deg C, 1 h, 2.) benzene, 40-45 deg C, 4 h 2: HCl / H2O / 1 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 52, # 3 p. 336 - 338
反应条件
1.1: 98 percent / imidazole / dimethylformamide / 0.5 h / 20 °C 2.1: MeLi; LiBr / diethyl ether; tetrahydrofuran / 0.08 h / -78 °C 2.2: s-BuLi / tetrahydrofuran; diethyl ether; cyclohexane / 0.08 h / -78 °C 2.3: 90 percent / tetrahydrofuran; diethyl ether; cyclohexane / -78 - 20 °C 3.1: 88 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Organic Preparations and Procedures International, , vol. 39, # 2 p. 199 - 202
反应条件
1.1: MeLi; LiBr / diethyl ether; tetrahydrofuran / 0.08 h / -78 °C 1.2: s-BuLi / tetrahydrofuran; diethyl ether; cyclohexane / 0.08 h / -78 °C 1.3: 90 percent / tetrahydrofuran; diethyl ether; cyclohexane / -78 - 20 °C 2.1: 88 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Organic Preparations and Procedures International, , vol. 39, # 2 p. 199 - 202
反应条件
(i) HCl, NaCl, CHCl3, Et2O, (ii) H2O; Multistep reaction;
参考文献
Chemische Berichte, , vol. 97, p. 312 - 324
反应条件
n-butyllithium; diethyl ether Behandeln des Reaktionsgemisches mit N-Methyl-formanilid in Aether;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 599, p. 131,132, 139
反应条件
hydrogenchloride; aluminium trichloride; benzene anfangs unter Kuehlung, schliesslich bei 35grad, man giesst das Reaktionsgemisch auf Eis, saeuert mit Salzsaeure an und destilliert mit Wasserdampf;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 357, p. 373
