(2R)-四氢-5-氧代-2beta-呋喃甲醛合成路线 （共 19 条）
反应条件
1: 96 percent / FeCl3*SiO2 / CH2Cl2 / 48 h / 20 °C
2: NaIO4 / CH2Cl2; H2O / 0.5 h / 0 °C
View Scheme
参考文献
Bernard, Angela M.; Frongia, Angelo; Piras, Pier P.; Secci, Francesco
Organic Letters, 2003 , vol. 5, # 16 p. 2923 - 2926
反应条件
1: H2 / 10 percent Pd/C / ethyl acetate / 1.5 h / 20 °C
2: NaIO4; silica gel / H2O; CH2Cl2 / 20 °C
View Scheme
参考文献
Nakada, Masahisa; Takano, Masashi; Iwata, Yukitaka
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 10 p. 1581 - 1585
反应条件
1: MeOLi; MeOH / hexane / 1 h / 0 °C
2: H2 / 10 percent Pd/C / ethyl acetate / 1.5 h / 20 °C
3: NaIO4; silica gel / H2O; CH2Cl2 / 20 °C
View Scheme
参考文献
Nakada, Masahisa; Takano, Masashi; Iwata, Yukitaka
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 10 p. 1581 - 1585
反应条件
1.1: O3 / CH2Cl2 / 1 h / -78 °C
1.2: 81 percent / Zn; 50 percent aq. AcOH / CH2Cl2 / -78 - 20 °C
2.1: MeOLi; MeOH / hexane / 1 h / 0 °C
3.1: H2 / 10 percent Pd/C / ethyl acetate / 1.5 h / 20 °C
4.1: NaIO4; silica gel / H2O; CH2Cl2 / 20 °C
View Scheme
参考文献
Nakada, Masahisa; Takano, Masashi; Iwata, Yukitaka
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 10 p. 1581 - 1585
反应条件
1: 1.) ozone, 2.) Me2S / 1.) MeOH, -78 deg C, 15 min, 2.) 4 h
2: 100 percent / H2 / 10percent Pd/C / ethyl acetate
3: 0.9 g / PCC
View Scheme
参考文献
Chattopadhyay, S.; Mamdapur, V. R.; Chadha, M. S.
Synthetic Communications, 1990 , vol. 20, # 9 p. 1299 - 1303
反应条件
1: 100 percent / H2 / 10percent Pd/C / ethyl acetate
2: 0.9 g / PCC
View Scheme
参考文献
Chattopadhyay, S.; Mamdapur, V. R.; Chadha, M. S.
Synthetic Communications, 1990 , vol. 20, # 9 p. 1299 - 1303
反应条件
silica gel in dichloromethane
0.25 h;
参考文献
Rassu, Gloria; Zanardi, Franca; Battistini, Lucia; Gaetani, Enrico; Casiraghi, Giovanni
Journal of Medicinal Chemistry, 1997 , vol. 40, # 2 p. 168 - 180
反应条件
1: 80percent aq. acetic acid / 8 h / 50 °C
2: 0.65 M aq. NaOIO4, SiO2 / CH2Cl2 / 0.25 h
View Scheme
参考文献
Rassu, Gloria; Zanardi, Franca; Battistini, Lucia; Gaetani, Enrico; Casiraghi, Giovanni
Journal of Medicinal Chemistry, 1997 , vol. 40, # 2 p. 168 - 180
反应条件
pyridinium chlorochromate
参考文献
Chattopadhyay, S.; Mamdapur, V. R.; Chadha, M. S.
Synthetic Communications, 1990 , vol. 20, # 9 p. 1299 - 1303
