4-[5-[[2-(氮杂环庚-1-基)-5-氰基-1-乙基-4-甲基-6-氧代-吡啶-3-基]亚甲基]-4-氧代-2-硫代-噻唑烷-3-基]丁酸合成路线 （共 24 条）
反应条件
in diethyl ether
T=-25°C;
参考文献
Cunico, Robert F.; Bedell, Louis
Journal of Organic Chemistry, 1983 , vol. 48, # 16 p. 2780 - 2782
反应条件
in chloroform-d1
acetonitrile was added in 6 portions during two weeks;
参考文献
De Sarlo, Francesco; Guarna, Antonio; Brandi, Alberto
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1505 - 1507
反应条件
triethylamine in benzene
T=70°C; 2 h; Microwave irradiation; regioselective reaction;
参考文献
Lasri, Jamal; Mukhopadhyay, Suman; Charmier, M. Adilia Januario
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 5 p. 1385 - 1389
反应条件
triethylamine in benzene
T=70°C; 2 h; Microwave irradiation; regioselective reaction;
参考文献
Lasri, Jamal; Mukhopadhyay, Suman; Charmier, M. Adilia Januario
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 5 p. 1385 - 1389
