4,2':6',4''-三联吡啶合成路线 （共 5 条）
反应条件
C35H50I2N2O2PPd; caesium carbonate in 1,4-dioxane
T=110°C; Suzuki Coupling; 12 h; Inert atmosphere;
参考文献
Xu, Chen; Hao, Xin-Qi; Li, Zhen; Duan, Lu-Meng; Wang, Zhi-Qiang; Ji, Bao-Ming; Song, Mao-Ping
Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 10 p. 3430 - 3432
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethanol; water; toluene
T=90°C; 24 h; Inert atmosphere;
参考文献
Zheng, Yao-Rong; Yang, Hai-Bo; Ghosh, Koushik; Zhao, Liang; Stang, Peter J.
Chemistry - A European Journal, 2009 , vol. 15, # 29 p. 7203 - 7214
反应条件
potassium hydroxide; tetrabutylammomium bromide; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
4 h; Heating;
参考文献
Ishikura; Ohta; Terashima
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 11 p. 4755 - 4763
反应条件
hydrogenchloride; ethanol; hydroxylamine
T=160 - 165°C;
参考文献
Magidson
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 165,171; engl. Ausg. S. 168, 173
反应条件
1: aqueous ethanol / Erwaermen des Reaktionsprodukts mit wss. HCl
2: NH2OH+HCl; aqueous ethanol / 160 - 165 °C
View Scheme
参考文献
Magidson
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 165,171; engl. Ausg. S. 168, 173
