3,5-二甲基-1-金刚烷醇合成路线 （共 28 条）
反应条件
1: With sodium hydroxide in diethylene glycol T=105 - 170°C; 10 h; 2: With hydrogenchloride in water; toluene T=5 - 15°C; 2.5 h; Product distribution / selectivity;
参考文献
WO2008/62472 A2, ;
Page/Page column 16-17 ;
反应条件
1: 79 percent / NaOH; H2O / dioxane / 20 h / 180 °C 2: 0.24 g / H2 / PtO2 / acetic acid / 7 h View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 23 p. 3527 - 3530
反应条件
formamide T=155°C; 8 h; Product distribution / selectivity;
参考文献
WO2006/122238 A1, ;
Page/Page column 14-15 ;
反应条件
2-hydroxy-1,3-isoindolinedione; cobalt(II) 2,4-pentanedionate in acetonitrile T=75°C; P=760 Torr; 3 h; Product distribution; Further Variations:Solvents;
参考文献
Tetrahedron Letters, , vol. 47, # 31 p. 5459 - 5461
反应条件
oxygen; sodium nitrite T=20°C; 3 h; Title compound not separated from byproducts.;
参考文献
Synlett, , # 15 p. 2415 - 2418
反应条件
pyridine; carbon tetrabromide; water; Mn(III) acetylacetonate Heating; Catalytic behavior; ConcentrationTemperatureTime;
参考文献
Russian Journal of Organic Chemistry, , vol. 50, # 1 p. 25 - 28
Zh. Org. Khim., , vol. 50, # 1 p. 33 - 36,4
反应条件
1: hydrogenchloride / water / 15 h / 25 - 30 °C 2: 8 h / 150 °C 3: hydrogenchloride / water / 100 - 105 °C View Scheme
参考文献
Reddy, Jambula Mukunda; Prasad, Ganji; Raju, Veeramalla; Ravikumar, Mylavarapu; Himabindu, Vurumidi; Reddy, Ghanta Mahesh
Organic Process Research and Development, 2007 , vol. 11, # 2 p. 268 - 269
反应条件
1: hydrogenchloride / water / 15 h / 25 - 30 °C 2: 8 h / 150 °C View Scheme
参考文献
Reddy, Jambula Mukunda; Prasad, Ganji; Raju, Veeramalla; Ravikumar, Mylavarapu; Himabindu, Vurumidi; Reddy, Ghanta Mahesh
Organic Process Research and Development, 2007 , vol. 11, # 2 p. 268 - 269
反应条件
hydrogen bromide in water 0.666667 h; Inert atmosphere;
参考文献
Kobayashi, Shoji; Kuroda, Hiroyuki; Ohtsuka, Yuta; Kashihara, Takashi; Masuyama, Araki; Watanabe, Kiyoshi
Tetrahedron, 2013 , vol. 69, # 10 p. 2251 - 2259
反应条件
hydrogenchloride in water T=25 - 30°C; 15 h;
参考文献
Reddy, Jambula Mukunda; Prasad, Ganji; Raju, Veeramalla; Ravikumar, Mylavarapu; Himabindu, Vurumidi; Reddy, Ghanta Mahesh
Organic Process Research and Development, 2007 , vol. 11, # 2 p. 268 - 269
