4-溴-N,N-二甲基苯磺酰胺合成路线 （共 5 条）
反应条件
1: dimethyl amine With triethylamine in tetrahydrofuran; dichloromethane T=0°C; 2: 4-bromobenzenesulfonyl chloride in tetrahydrofuran; dichloromethane T=20°C;
参考文献
ELI LILLY AND COMPANY
Patent: WO2004/9086 A1, 2004 ;
Location in patent: Page/Page column 60 ;
WO 2004/009086 A1
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=20°C; 5.5 h;
参考文献
MERCK and CO., INC.; SUNESIS PHARMACEUTICALS, INC.
Patent: WO2006/44497 A2, 2006 ;
Location in patent: Page/Page column 130 ;
WO 2006/044497 A2
反应条件
copper diacetate; 3-phenyl-2-propenoic acid; copper(l) chloride T=110°C; 24 h;
参考文献
Huang, Xin; Wang, Jichao; Ni, Zhangqin; Wang, Sichang; Pan, Yuanjiang
Chemical Communications, 2014 , vol. 50, # 35 p. 4582 - 4584
反应条件
Product distribution;
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. 331, # 6 p. 1011 - 1013
反应条件
1: With potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in dimethyl sulfoxide T=20 - 90°C; 8 h; 2: With water in dimethyl sulfoxide
参考文献
WO2004/9086 A1, ;
Page/Page column 60 ;
WO 2004/009086 A1
