1: 1-Bromo-2-isopropyl-benzene With potassium hydroxide; tris-(dibenzylideneacetone)dipalladium(0); di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine in 1,4-dioxane; water T=100°C; 6 h; 2: isopropyl bromide With N-hexadecyl-N,N,N-trimethylammonium bromide in 1,4-dioxane; water T=100°C; 1 h;
参考文献
Anderson, Kevin W.; Ikawa, Takashi; Tundel, Rachel E.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2006 , vol. 128, # 33 p. 10694 - 10695
n-butyllithium in tetrahydrofuran; hexane T=160°C;
参考文献
Zhi, Lin; Tegley, Christopher M.; Pio, Barbara; Edwards, James P.; Motamedi, Mehrnouch; Jones, Todd K.; Marschke, Keith B.; Mais, Dale E.; Risek, Boris; Schrader, William T.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 19 p. 4104 - 4112
potassium hydroxide; tris-(dibenzylideneacetone)dipalladium(0); di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine in 1,4-dioxane; water T=100°C; 6 h;
参考文献
Anderson, Kevin W.; Ikawa, Takashi; Tundel, Rachel E.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2006 , vol. 128, # 33 p. 10694 - 10695
1: With tert.-butyl lithium in tetrahydrofuran; pentane T=-78°C; Inert atmosphere; 2: With tri-isopropoxy-borane in tetrahydrofuran; pentane T=-78 - 20°C; 3: With hydrogenchloride in tetrahydrofuran; water; pentane 0.5 h;
参考文献
Zehm, Daniel; Fudickar, Werner; Hans, Melanie; Schilde, Uwe; Kelling, Alexandra; Linker, Torsten
Chemistry - A European Journal, 2008 , vol. 14, # 36 p. 11429 - 11441
