反应条件
1.1: NaHMDS / 1,2-dimethoxy-ethane
1.2: 50 percent / 1,2-dimethoxy-ethane
2.1: (S)-BINAL-H; LiAlH4 / tetrahydrofuran
3.1: K2CO3; MeOH
4.1: p-TSA / CH2Cl2
5.1: DIBAL-H / -78 °C
6.1: NaHMDS
7.1: aq. AcOH / tetrahydrofuran
View Scheme
参考文献
DeLong, Mitchell A.; Amburgey, Jack; Taylor, Cynthia; Wos, John A.; Soper, David L.; Wang, Yili; Hicks, Renee
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1519 - 1522
