3-溴-5-乙基-2-羟基苯甲醛合成路线 （共 2 条）
反应条件
bromine; sodium acetate; acetic acid
T=50°C; 12 h;
参考文献
McGarrigle; Murphy; Gilheany
Tetrahedron Asymmetry, 2004 , vol. 15, # 8 p. 1343 - 1354
反应条件
1.1: Mg(OMe)2 / methanol
1.2: methanol; toluene / 2 h / 95 - 105 °C
1.3: 80 percent / aq. H2SO4 / methanol; toluene / 2 h / 50 °C
2.1: 88 percent / glacial acetic acid; NaOAc; Br2 / 12 h / 50 °C
View Scheme
参考文献
McGarrigle; Murphy; Gilheany
Tetrahedron Asymmetry, 2004 , vol. 15, # 8 p. 1343 - 1354
