1-氟-3-苯基-2-丙胺合成路线 （共 2 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol
P=2280.15 Torr; 2 h;
参考文献
Gurley, David; Rosamond, James
Patent: US2005/245595 A1, 2005 ;
Location in patent: Page/Page column 10 ;
反应条件
1: in diethyl ether
T=-20°C; Addition; 0.5 h;
2: With sodium tetrahydroborate in methanol; water
T=-20 - 0°C; Reduction; 2 h;
参考文献
Grunewald, Gary L.; Caldwell, Timothy M.; Li, Qifang; Slavica, Men; Criscione, Kevin R.; Borchardt, Ronald T.; Wang, Wen
Journal of Medicinal Chemistry, 1999 , vol. 42, # 18 p. 3588 - 3601
