1.1: 88 percent / I2; PPh3; imidazole 2.1: 98 percent / dioxane / 100 °C 3.1: 99 percent / toluene 4.1: NaOEt / ethanol / Heating 5.1: o-(NO2)C6H4SeCN; PBu3 / tetrahydrofuran 5.2: aq. H2O2 / tetrahydrofuran 6.1: 61 percent / MeLi / 0 °C 7.1: TBAF 8.1: PCC 9.1: 82 percent / NaH / tetrahydrofuran / 20 °C 10.1: 87 percent / AD-mix-α / 0 - 20 °C 11.1: MeC(OMe)3; PPTS / CH2Cl2 11.2: 88 percent / TMSCl; K2CO3 / methanol 12.1: DIBAL-H / toluene 13.1: DMF / 160 °C View Scheme

1.1: 88 percent / I2; PPh3; imidazole 2.1: 98 percent / dioxane / 100 °C 3.1: 99 percent / toluene 4.1: NaOEt / ethanol / Heating 5.1: o-(NO2)C6H4SeCN; PBu3 / tetrahydrofuran 5.2: aq. H2O2 / tetrahydrofuran 6.1: 61 percent / MeLi / 0 °C 7.1: TBAF 8.1: PCC 9.1: 82 percent / NaH / tetrahydrofuran / 20 °C 10.1: 87 percent / AD-mix-α / 0 - 20 °C 11.1: MeC(OMe)3; PPTS / CH2Cl2 11.2: 88 percent / TMSCl; K2CO3 / methanol 12.1: DIBAL-H / toluene 13.1: DMF / 160 °C View Scheme

1.1: 88 percent / I2; PPh3; imidazole 2.1: 98 percent / dioxane / 100 °C 3.1: 99 percent / toluene 4.1: NaOEt / ethanol / Heating 5.1: o-(NO2)C6H4SeCN; PBu3 / tetrahydrofuran 5.2: aq. H2O2 / tetrahydrofuran 6.1: 61 percent / MeLi / 0 °C 7.1: TBAF 8.1: PCC 9.1: 82 percent / NaH / tetrahydrofuran / 20 °C 10.1: 87 percent / AD-mix-α / 0 - 20 °C 11.1: MeC(OMe)3; PPTS / CH2Cl2 11.2: 88 percent / TMSCl; K2CO3 / methanol 12.1: DIBAL-H / toluene 13.1: DMF / 160 °C View Scheme