1.1: 99 percent / toluene 2.1: NaOEt / ethanol / Heating 3.1: o-(NO2)C6H4SeCN; PBu3 / tetrahydrofuran 3.2: aq. H2O2 / tetrahydrofuran 4.1: 61 percent / MeLi / 0 °C 5.1: TBAF 6.1: PCC 7.1: 82 percent / NaH / tetrahydrofuran / 20 °C 8.1: 87 percent / AD-mix-α / 0 - 20 °C 9.1: MeC(OMe)3; PPTS / CH2Cl2 9.2: 88 percent / TMSCl; K2CO3 / methanol 10.1: DIBAL-H / toluene 11.1: DMF / 160 °C View Scheme

1.1: 99 percent / toluene 2.1: NaOEt / ethanol / Heating 3.1: o-(NO2)C6H4SeCN; PBu3 / tetrahydrofuran 3.2: aq. H2O2 / tetrahydrofuran 4.1: 61 percent / MeLi / 0 °C 5.1: TBAF 6.1: PCC 7.1: 82 percent / NaH / tetrahydrofuran / 20 °C 8.1: 87 percent / AD-mix-α / 0 - 20 °C 9.1: MeC(OMe)3; PPTS / CH2Cl2 9.2: 88 percent / TMSCl; K2CO3 / methanol 10.1: DIBAL-H / toluene 11.1: DMF / 160 °C View Scheme

1.1: 99 percent / toluene 2.1: NaOEt / ethanol / Heating 3.1: o-(NO2)C6H4SeCN; PBu3 / tetrahydrofuran 3.2: aq. H2O2 / tetrahydrofuran 4.1: 61 percent / MeLi / 0 °C 5.1: TBAF 6.1: PCC 7.1: 82 percent / NaH / tetrahydrofuran / 20 °C 8.1: 87 percent / AD-mix-α / 0 - 20 °C 9.1: MeC(OMe)3; PPTS / CH2Cl2 9.2: 88 percent / TMSCl; K2CO3 / methanol 10.1: DIBAL-H / toluene 11.1: DMF / 160 °C View Scheme