2-苯基咪唑并(2,1-a)异喹啉合成路线 （共 19 条）
反应条件
1: 64 percent / 2.) 70percent HClO4 / 1.) ether, room temp., 24 h
2: 65 percent / H2NOH*HCl, CH3COONa / aq. acetic acid
3: 70 percent / 10percentPd/C / 1 h / 190 °C
View Scheme
参考文献
Mohrle; Grimm
Archiv der Pharmazie, 1986 , vol. 319, # 4 p. 325 - 332
反应条件
1: 64 percent / 2.) 70percent HClO4 / 1.) ether, room temp., 24 h
2: 65 percent / H2NOH*HCl, CH3COONa / aq. acetic acid
3: 70 percent / 10percentPd/C / 1 h / 190 °C
View Scheme
参考文献
Mohrle; Grimm
Archiv der Pharmazie, 1986 , vol. 319, # 4 p. 325 - 332
反应条件
sodium carbonate in acetonitrile
T=20°C; 1 h;
参考文献
Hou; Wang; Huang; Chen
Organic Preparations and Procedures International, 2004 , vol. 36, # 5 p. 491 - 494
反应条件
1: acetonitrile / 1 h / Heating
2: Na2CO3 / acetonitrile / 1 h / 20 °C
View Scheme
参考文献
Hou; Wang; Huang; Chen
Organic Preparations and Procedures International, 2004 , vol. 36, # 5 p. 491 - 494
反应条件
1: tetrahydrofuran / Ambient temperature
2: potassium carbonate / tetrahydrofuran / 72 h
View Scheme
参考文献
Ito, Suketaka; Kakehi, Akikazu; Miwa, Toshikazu
Heterocycles, 1991 , vol. 32, # 12 p. 2373 - 2380
反应条件
1: tetrahydrofuran / Ambient temperature
2: potassium carbonate / tetrahydrofuran / 72 h
View Scheme
参考文献
Ito, Suketaka; Kakehi, Akikazu; Miwa, Toshikazu
Heterocycles, 1991 , vol. 32, # 12 p. 2373 - 2380
反应条件
triethylamine
1.) acetone, rt, 3 d, 2.) DMF, heating, 12 h; Yield given. Multistep reaction;
参考文献
Artemov, V. A.; Shestopalov, A. M.; Litvinov, V. P.
Russian Journal of Organic Chemistry, 1995 , vol. 31, # 4 p. 548 - 553
Zhurnal Organicheskoi Khimii, 1995 , vol. 31, # 4 p. 595 - 600
反应条件
T=130°C; Beh. des Salzgemisches mit wss.-methanol. Ammoniak;
参考文献
Kroehnke; Zecher
Chemische Berichte, 1962 , vol. 95, p. 1128,1135
反应条件
hydrogen; palladium on activated charcoal in ethanol; acetic acid
T=90°C; P=7500.6 Torr; 3 h;
参考文献
Toja; Omodei Sale; Favara; Omodei-Sale; Cattaneo; Gallico; Galliani
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 9 p. 1222 - 1226
