N-异丙基-4-甲氧基苄基胺合成路线 （共 11 条）
反应条件
sodium hydroxide; sodium tris(acetoxy)borohydride; triethylamine in anhydrous dichloroethane; dichloromethane; acetone
参考文献
Munson, Mark; Mareska, David A.; Kim, Youngboo; Groneberg, Robert D.; Rizzi, James; Rodriguez, Martha; Kim, Ganghyeok; Vigers, Guy; Rao, Chang; Balachari, Devan; Harvey, Darren
Patent: US2004/192653 A1, 2004 ;
US 20040192653 A1
反应条件
[(C5Me5)IrI2]2 in anhydrous xylene
T=155°C; 10 h; Inert atmosphere;
参考文献
Saidi, Ourida; Williams, Jonathan M. J.; Blacker, A. John; Farah, Mohamed M.; Marsden, Stephen P.
Angewandte Chemie, International Edition, 2009 , vol. 48, # 40 p. 7375 - 7378
Angewandte Chemie, 2009 , vol. 121, # 40 p. 7511 - 7514
反应条件
sodium tetrahydroborate in methanol
2 h; Reflux;
参考文献
Stankovic, Sonja; D'Hooghe, Matthias; De Kimpe, Norbert
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 19 p. 4266 - 4273
反应条件
1: With manganese(IV) oxide; sodium tetrahydroborate in dichloromethane
Heating;
2: With methanol
T=0 - 20°C; 0.666667 h;
参考文献
Kanno, Hisashi; Taylor, Richard J.K.
Tetrahedron Letters, 2002 , vol. 43, # 41 p. 7337 - 7340
反应条件
lithium aluminium tetrahydride in diethyl ether
Reflux;
参考文献
Stankovic, Sonja; D'Hooghe, Matthias; De Kimpe, Norbert
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 19 p. 4266 - 4273
反应条件
tris(triphenylphosphine)ruthenium(II) chloride; sodium hydroxide
T=120°C; 20 h; Inert atmosphere;
参考文献
Werkmeister, Svenja; Bornschein, Christoph; Junge, Kathrin; Beller, Matthias
European Journal of Organic Chemistry, 2013 , # 18 p. 3671 - 3674
反应条件
aluminium; mercury dichloride in ethanol
T=100°C; 4 h;
参考文献
Angerer, Erwin von; Egginger, Guenter; Kranzfelder, Gerhard; Bernhauer, Horst; Schoenenberger, Helmut
Journal of Medicinal Chemistry, 1982 , vol. 25, # 7 p. 832 - 837
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=160°C; Microwave irradiation; regioselective reaction;
参考文献
Stankovic, Sonja; D'Hooghe, Matthias; De Kimpe, Norbert
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 19 p. 4266 - 4273
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=160°C; Microwave irradiation; regioselective reaction;
参考文献
Stankovic, Sonja; D'Hooghe, Matthias; De Kimpe, Norbert
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 19 p. 4266 - 4273
反应条件
1: CHCl3 / 1 h / Ambient temperature
2: Al, HgCl2 / ethanol / 4 h / 100 °C
View Scheme
参考文献
Angerer, Erwin von; Egginger, Guenter; Kranzfelder, Gerhard; Bernhauer, Horst; Schoenenberger, Helmut
Journal of Medicinal Chemistry, 1982 , vol. 25, # 7 p. 832 - 837
