6-氟-1H-吲唑-5-胺合成路线 （共 4 条）
反应条件
hydrogenchloride; tin(ll) chloride in water T=20°C; 5 h;
参考文献
Takami, Atsuya; Iwakubo, Masayuki; Okada, Yuji; Kawata, Takehisa; Odai, Hideharu; Takahashi, Nobuaki; Shindo, Kazutoshi; Kimura, Kaname; Tagami, Yoshimichi; Miyake, Mika; Fukushima, Kayoko; Inagaki, Masaki; Amano, Mutsuki; Kaibuchi, Kozo; Iijima, Hiroshi
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 9 p. 2115 - 2137
反应条件
1.1: potassium acetate / CHCl3 / 20 - 40 °C 1.2: isoamyl nitrite / CHCl3 / 18 h / 60 °C 2.1: 4.80 g / HCl / methanol / 5 h / 80 °C 3.1: 3.00 g / sodium nitrate; H2SO4 / H2O / 1 h / 20 °C 4.1: 1.67 g / SnCl2*2H2O; HCl / H2O / 5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 9 p. 2115 - 2137
反应条件
1: 3.00 g / sodium nitrate; H2SO4 / H2O / 1 h / 20 °C 2: 1.67 g / SnCl2*2H2O; HCl / H2O / 5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 9 p. 2115 - 2137
反应条件
1: 4.80 g / HCl / methanol / 5 h / 80 °C 2: 3.00 g / sodium nitrate; H2SO4 / H2O / 1 h / 20 °C 3: 1.67 g / SnCl2*2H2O; HCl / H2O / 5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 9 p. 2115 - 2137
