sulfuric acid

tetrakis(triphenylphosphine) palladium(0); potassium carbonate in N,N-dimethyl-formamide Suzuki coupling;

water; triethylamine; Pd(OAc)2EnCatTM in N,N-dimethyl-formamide T=85°C; Suzuki-Miyaura reaction;

1: 4-iodobenzoic acid ethyl ester With copper; zinc in N,N-dimethyl-formamide T=100°C; 0.166667 h; 2: 4-bromo-benzaldehyde With bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide T=120°C; Negishi cross-coupling reaction; 0.0833333 h; Further stages.;

Diazotization.anschliessende Umsetzung mit Benzaldehyd;

hydrogenchloride Combinatorial reaction / High throughput screening (HTS); Product distribution / selectivity;

1: With trichloroacetic acid in dichloromethane 17 h; 2: With chloranil in dichloromethane 3 h;