5-乙酰基-2-溴苯甲酸甲酯合成路线 （共 3 条）
反应条件
ammonium hydroxide in tetrahydrofuran
Ambient temperature; Yield given;
参考文献
Fujikura; Miigata; Hashimoto; Imai; Takenaka
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 11 p. 4092 - 4101
反应条件
1: 1.) NaNO2, cc HCl 2.) CuCl2*2H2O, SO2 / 1.) AcOH, 5 deg C, 30 min 2.) AcOH, 0-5 deg C
2: cc NH4OH / tetrahydrofuran / Ambient temperature
View Scheme
参考文献
Fujikura; Miigata; Hashimoto; Imai; Takenaka
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 11 p. 4092 - 4101
反应条件
1: Br2, AcOH
2: (i), (ii) NaBH4, (iii) H2, Pd-C
View Scheme
参考文献
Yamanouchi Pharm.
Patent: DE2843016 , 1979 ;
Chem.Abstr., 1979 , vol. 91, # 157445
