2,2,2-三氟-1-(2-羟基-5-甲基苯基)-乙酮合成路线 （共 3 条）
反应条件
1: With AlCl3, aluminium chloride
T=20 - 100°C; Fries rearrangement; Neat (no solvent);
2: With hydrogenchloride in water
T=20°C;
参考文献
Sevenard, Dmitri V.; Vorobyev, Mikhail; Sosnovskikh, Vyacheslav Ya.; Wessel, Helma; Kazakova, Olesya; Vogel, Vera; Shevchenko, Nikolay E.; Nenajdenko, Valentine G.; Lork, Enno; Roeschenthaler, Gerd-Volker
Tetrahedron, 2009 , vol. 65, # 36 p. 7538 - 7552
反应条件
(i) AlCl3, CS2, (ii) /BRN= 3595638/, aq. NH3; Multistep reaction;
参考文献
May and Baker
Patent: DE2846931 , 1979 ;
Chem.Abstr., 1979 , vol. 91, # 74626
反应条件
1: 44 percent / conc. HNO3, conc. H2SO4 / -20 °C
2: 57 percent / H2 / 5percent Pd/C / ethanol
View Scheme
参考文献
May and Baker
Patent: DE2846931 , 1979 ;
Chem.Abstr., 1979 , vol. 91, # 74626
