4-(2-甲氧基乙氧基)哌啶盐酸盐合成路线 （共 4 条）
反应条件
sodium hydride in N,N-dimethyl-formamide; paraffin
Ambient temperature;
参考文献
Campbell, Simon F.; Danilewicz, John C.; Greengrass, Colin W.; Plews, Rhona M.
Journal of Medicinal Chemistry, 1988 , vol. 31, p. 516 - 520
反应条件
potassium hydroxide in water
24 h; Heating; Yield given;
参考文献
Baker, William R.; Fung, Anthony K. L.; Kleinert, Hollis D.; Stein, Herman H.; Plattner, Jacob J.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1722 - 1734
反应条件
1: 16 h / Ambient temperature
2: 1.) NaH / 1.) THF, RT, 2 h, 2.) THF, RT, 16 h
3: KOH / H2O / 24 h / Heating
View Scheme
参考文献
Baker, William R.; Fung, Anthony K. L.; Kleinert, Hollis D.; Stein, Herman H.; Plattner, Jacob J.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1722 - 1734
反应条件
1: 1.) NaH / 1.) THF, RT, 2 h, 2.) THF, RT, 16 h
2: KOH / H2O / 24 h / Heating
View Scheme
参考文献
Baker, William R.; Fung, Anthony K. L.; Kleinert, Hollis D.; Stein, Herman H.; Plattner, Jacob J.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1722 - 1734
