3,5-双(甲基硫代)吡啶合成路线 （共 7 条）
反应条件
2-mercaptoethanesulphonic acid sodium salt in N,N-dimethyl-formamide
T=80°C; 15 h;
参考文献
Testaferri, Lorenzo; Tiecco, Marcello; Tingoli, Marco; Bartoli, Donatella; Massoli, Alberto
Tetrahedron, 1985 , vol. 41, # 7 p. 1373 - 1384
反应条件
in N,N-dimethyl-formamide
T=80°C;
参考文献
Tiecco, Marcello
Bulletin des Societes Chimiques Belges, 1986 , vol. 95, # 11 p. 1009 - 1020
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
1) 0.5h, r.t. 2) 12h, reflux;
参考文献
Chen, Ted K.; Flowers, William T.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 4 p. 831 - 833
反应条件
1: tributylphosphine
2: LiAlH4
View Scheme
参考文献
Chen, Ted K.; Flowers, William T.
Journal of the Chemical Society, Chemical Communications, 1980 , # 23 p. 1139 - 1140
反应条件
sodium
1.) HMPA, 120 deg C, 2-4 h; 2.) RT, 30 min; Yield given. Multistep reaction;
参考文献
Testaferri, Lorenzo; Tiecco, Marcello; Tingoli, Marco; Bartoli, Donatella; Massoli, Alberto
Tetrahedron, 1985 , vol. 41, # 7 p. 1373 - 1384
反应条件
1: NaNO2-HCl
2: tributylphosphine
3: LiAlH4
View Scheme
参考文献
Chen, Ted K.; Flowers, William T.
Journal of the Chemical Society, Chemical Communications, 1980 , # 23 p. 1139 - 1140
反应条件
sodium hypochlorite
2 h; Ambient temperature;
参考文献
Woods, S. G.; Matyas, B. T.; Vinogradoff, A. P.; Tong, Y. C.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 1 p. 97 - 101
