(1-氧基-2,2,5,5,-四甲基-?3-吡咯啉)甲醛合成路线 （共 21 条）
反应条件
1: With boron trifluoride diethyl etherate in dichloromethane T=20°C; 1 h; 2: With triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone in dichloromethane T=20°C; 1 h; Further stages.;
参考文献
Synthesis, , # 15 p. 2573 - 2579
反应条件
sodium ethanolate T=0°C; 2 h;
参考文献
Mustafi, Devkumar; Boisvert, William E.; Makinen, Marvin W.
Journal of the American Chemical Society, 1993 , vol. 115, # 9 p. 3674 - 3682
反应条件
in tetrahydrofuran 3 h; Heating;
参考文献
Hankovszky, H. Olga; Hideg, Kalman; Lex, Laszlo; Kulcsar, Gyula; Halasz, H. Anna
Canadian Journal of Chemistry, 1982 , vol. 60, p. 1432 - 1438
反应条件
1.) DMF, 40 degC, 3 d, 2.) DMF, acetic acid, 80 degC, 2 d;
参考文献
Hankovszky, H. Olga; Hideg, Kalman; Lex, Laszlo; Kulcsar, Gyula; Halasz, H. Anna
Canadian Journal of Chemistry, 1982 , vol. 60, p. 1432 - 1438
反应条件
Horner-Emmons reaction;
参考文献
Kalai, Tamas; Bognar, Balazs; Jeko, Jozsef; Hideg, Kalman
Synthesis, 2006 , # 15 p. 2573 - 2579
反应条件
sodium hydroxide; dihydrogen peroxide in methanol T=20°C; 24 h;
参考文献
Kalai, Tamas; Sar, Cecilia P.; Jeko, Jozsef; Hideg, Kalman
Tetrahedron Letters, 2002 , vol. 43, # 45 p. 8125 - 8127
反应条件
sodium hydroxide in ethanol T=25°C; 3 h;
参考文献
Hankovszky, H. Olga; Hideg, Kalman; Jerkovich, Gyula
Synthesis, 1989 , # 7 p. 526 - 529
反应条件
lithium tri-t-butoxyaluminum hydride in tetrahydrofuran
T=-70°C; 1 h; Yield given;
参考文献
Mustafi, Devkumar; Boisvert, William E.; Makinen, Marvin W.
Journal of the American Chemical Society, 1993 , vol. 115, # 9 p. 3674 - 3682
反应条件
diisobutylaluminium hydride in tetrahydrofuran
T=-60°C; 1 h;
参考文献
Stork, Sebastian W.; Makinen, Marvin W.
Synthesis, 1999 , # 8 p. 1309 - 1312
反应条件
1: SOCl2; pyridine / benzene
2: LiAlH(O-t-Bu)3 / tetrahydrofuran / -78 - 20 °C
View Scheme
参考文献
Ozhogina, Olga A
Tetrahedron Letters, 2002 , vol. 43, # 4 p. 553 - 555
