四氢-2-(11-十四碳炔基氧基)-2H-吡喃合成路线 （共 10 条）
反应条件
toluene-4-sulfonic acid in methanol 2 h; Heating; Yield given;
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
反应条件
1: 3.0 g / TsOH / methanol; H2O / 20 h 2: LiAlH4 / tetrahydrofuran; bis-(2-methoxy-ethyl) ether / 36 h / 140 °C 3: 1.3 g / pyridine / 24 h / Ambient temperature View Scheme
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
反应条件
1: 3.0 g / TsOH / methanol; H2O / 20 h 2: LiAlH4 / tetrahydrofuran; bis-(2-methoxy-ethyl) ether / 36 h / 140 °C View Scheme
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
反应条件
n-butyllithium
1.) hexane, HMPT, 0 deg C, 30 min, 2.) 20 deg C, 12 h; Multistep reaction;
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
反应条件
1: p-TsOH / diethyl ether
2: 51 percent / dimethylsulfoxide / 16 h / Ambient temperature
3: 1.) 2M BuLi / 1.) hexane, HMPT, 0 deg C, 30 min, 2.) 20 deg C, 12 h
View Scheme
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
反应条件
1: p-TsOH / diethyl ether
2: 51 percent / dimethylsulfoxide / 16 h / Ambient temperature
3: 1.) 2M BuLi / 1.) hexane, HMPT, 0 deg C, 30 min, 2.) 20 deg C, 12 h
View Scheme
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
反应条件
1: 51 percent / dimethylsulfoxide / 16 h / Ambient temperature
2: 1.) 2M BuLi / 1.) hexane, HMPT, 0 deg C, 30 min, 2.) 20 deg C, 12 h
View Scheme
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
反应条件
ammonia; iron(III) chloride; lithium
1) -35 deg C, 1 h, 2) THP, DMSO, -40 deg C, 2 h; Multistep reaction;
参考文献
Odinokov; Botsman; Gladysheva
Chemistry of Natural Compounds, 1996 , vol. 32, # 3 p. 381 - 383
反应条件
1: p-TsOH / methanol / 2 h / Heating
2: 95 percent / H2, quinoline / Lindlar catalyst / pentane / 1 h / -10 °C
View Scheme
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
反应条件
1: p-TsOH / methanol / 2 h / Heating
2: 95 percent / H2, quinoline / Lindlar catalyst / pentane / 1 h / -10 °C
3: 95 percent / pyridine / diethyl ether
View Scheme
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
