5-氨基吲哚-2-甲酸乙酯合成路线 （共 13 条）
反应条件
ammonium formate; palladium on activated carbon in ethanol 0.5 h; Heating / reflux;
参考文献
WO2005/80367 A1, ;
Page/Page column 67-68; 113-114 ;
参考文献
US2011/224137 A1, ;
US 20110224137 A1
反应条件
hydrogenchloride Erwaermen des Reaktionsprodukts mit aethanol. HCl;
参考文献
Journal of Organic Chemistry, , vol. 18, p. 345,356
反应条件
1: PCl / Behandeln des Reaktionsprodukts mit NaN3 in wss. Aceton und Erhitzen in Toluol 2: concentrated aqueous HCl / Erwaermen des Reaktionsprodukts mit aethanol. HCl View Scheme
参考文献
Journal of Organic Chemistry, , vol. 18, p. 345,356
反应条件
D-glucose 1.) methanol, reflux, 2 h; 2.) pyridine, 20 deg C, 12 h; Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 22, # 9 p. 1678 - 1682
Zhurnal Organicheskoi Khimii, , vol. 22, # 9 p. 1868 - 1873
反应条件
1.) methanol, reflux; 2.) pyridine; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 22, # 9 p. 1678 - 1682
Zhurnal Organicheskoi Khimii, , vol. 22, # 9 p. 1868 - 1873
反应条件
1.) methanol, reflux, 2 h; 2.) pyridine, 20 deg C, 12 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 22, # 9 p. 1678 - 1682
Zhurnal Organicheskoi Khimii, , vol. 22, # 9 p. 1868 - 1873
反应条件
1.) methanol, reflux; 2.) pyridine; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 22, # 9 p. 1678 - 1682
Zhurnal Organicheskoi Khimii, , vol. 22, # 9 p. 1868 - 1873
反应条件
1: ethyl dimethylaminopropylcarbodiimide / dimethylformamide View Scheme
参考文献
Rajeswari; Adesomoju; Cava
Journal of Heterocyclic Chemistry, 1989 , vol. 26, # 3 p. 557 - 564
反应条件
1: (i-Pr)2NEt, DMAP / tetrahydrofuran / 16 h / -98 - 0 °C 2: aq. NaOH, pyridine / 103 h / 25 - 55 °C 3: EDC, DMA / 2 h / 25 °C View Scheme
参考文献
Mitchell; Kelly; Wicnienski; Hatzenbuhler; Williams; Petzold; Slightom; Siemieniak
Journal of the American Chemical Society, 1991 , vol. 113, # 23 p. 8994 - 8995
