3,4-二羟基-6-氟苯甲醛合成路线 (共 2 条)
反应条件
boron tribromide in dichloromethane
T=-78 - 20°C; Inert atmosphere;
参考文献
Yang, John; Marriner, Gwendolyn A.; Wang, Xinyu; Bowman, Phillip D.; Kerwin, Sean M.; Stavchansky, Salomon
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 14 p. 5032 - 5038
反应条件
1: 71 percent / cesium carbonate / dimethylformamide / 3 h / 110 °C
2: 67 percent / AcONH4 / 5 h / Heating
3: 51 percent / LiAlH4 / tetrahydrofuran
View Scheme
参考文献
Moreau, Anne; Couture, Axel; Deniau, Eric; Grandclaudon, Pierre; Lebrun, Stephane
Tetrahedron, 2004 , vol. 60, # 29 p. 6169 - 6176