乙基3-(3-硝基苯基)丙酸酯合成路线 （共 7 条）
反应条件
1: With water; sodium hydroxide in ethanol Reflux; 2: With hydrogenchloride in water
参考文献
Laboratorios Almirall, S.A.
Patent: EP2096105 A1, 2009 ;
Location in patent: Page/Page column 31 ;
反应条件
water; lithium chloride in dimethyl sulfoxide
T=170°C; 5 h;
参考文献
Laboratorios Almirall, S.A.
Patent: EP2096105 A1, 2009 ;
Location in patent: Page/Page column 30 ;
反应条件
1: 3-(bromo)propionic acid ethyl ester With indium; copper(l) iodide; lithium chloride in tetrahydrofuran
T=65°C; 12 h;
2: 1-iodo-3-nitro-benzene With tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl acetamide
T=90°C; 24 h;
参考文献
Shen, Zhi-Liang; Goh, Kelvin Kau Kiat; Wong, Colin Hong An; Yang, Yong-Sheng; Lai, Yin-Chang; Cheong, Hao-Lun; Loh, Teck-Peng
Chemical Communications, 2011 , vol. 47, # 16 p. 4778 - 4780
反应条件
potassium diazodicarboxylate
参考文献
Peng, Weimin; Blagg, Brian S. J.
Organic Letters, 2006 , vol. 8, # 5 p. 975 - 978
反应条件
palladium on activated charcoal; hydrogen
参考文献
Hao, Yan; Yang, Xichuan; Cong, Jiayan; Tian, Haining; Hagfeldt, Anders; Sun, Licheng
Chemical Communications, 2009 , # 27 p. 4031 - 4033
反应条件
1: sodium hydride / tetrahydrofuran
2: sodium chloride / dimethyl sulfoxide
View Scheme
参考文献
Jayasekara, P. Suresh; Barrett, Matthew O.; Ball, Christopher B.; Brown, Kyle A.; Hammes, Eva; Balasubramanian, Ramachandran; Harden, T. Kendall; Jacobson, Kenneth A.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 9 p. 3874 - 3883
反应条件
diisobutylaluminium hydride
参考文献
Jayasekara, P. Suresh; Barrett, Matthew O.; Ball, Christopher B.; Brown, Kyle A.; Hammes, Eva; Balasubramanian, Ramachandran; Harden, T. Kendall; Jacobson, Kenneth A.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 9 p. 3874 - 3883
